Organism

A clade of bacterial species previously categorized as Clostridium was recently renamed Enterocloster, now including Enterocloster clostridioforme, Enterocloster aldenense, Enterocloster asparagiforme, Enterocloster bolteae, Enterocloster citroniae and Enterocloster lavalense (Hass and Blanchard, 2020). These species are obligatory anaerobic, Gram-positive, rod-shaped organisms isolated from the gut microbiome ( Mohan, et al. 2006, Finegold, et al. 2005, Warren, et al. 2006).

Map

A collection of 115 reference genomes were downloaded from the NCBI Genome database on December 17, 2021 as part of a general survey of the normal human microbiota.

Notes

Looking across the genus as a whole, we can see clear delineation between the named species E. clostridioformis (or E. clostridioforme), E. boltae, E. aldenensis, E. citroniae, E. lavalensis, and E. asparagiformis. However, in the detailed region shown below we can see that the two species E. clostridioformis and E. boltae are much more similar to each other than to the other species in the genus. There is a group of genes (defined at the 80% amino acid similarity threshold) which is shared between isolates from these two species, but not with the other species. In addition, within each of those two species there appears to be two primary grouping of isolates, both in terms of ANI and gene content. All four of those groups are marked with orange boxes in the expanded image below. You can inspect that same region of the map by clicking and dragging over the indicated region using the live version above.

The orange box below indicates the region of the total map which is shown in the expanded details above.