This plot is meant to be functionally equivalent to Fig 5b (for HeLa, equivalent of Fig 3d for PC9). Volcano plot of target-level GI scores Blue points are synthetic lethal paralog GIs with GI < 0.5 and FDR < 0.1; red points are buffering paralog GIs with GI > 0.25 and FDR < 0.1.
plot_volcano(gimap_dataset, facet_rep = TRUE, reps_to_drop = "")
if (FALSE) { # \dontrun{
gimap_dataset <- get_example_data("gimap") %>%
gimap_filter() %>%
gimap_annotate(cell_line = "HELA") %>%
gimap_normalize(
timepoints = "day"
) %>%
calc_gi()
# To plot results
plot_exp_v_obs_scatter(gimap_dataset, reps_to_drop = "Day05_RepA_early")
plot_rank_scatter(gimap_dataset, reps_to_drop = "Day05_RepA_early")
plot_volcano(gimap_dataset, reps_to_drop = "Day05_RepA_early")
} # }